Vipie: web pipeline for parallel characterization of viral populations from multiple NGS samples.

ABSTRACT:

Background

Next generation sequencing (NGS) technology allows laboratories to investigate virome composition in clinical and environmental samples in a culture-independent way. There is a need for bioinformatic tools capable of parallel processing of virome sequencing data by exactly identical methods: this is especially important in studies of multifactorial diseases, or in parallel comparison of laboratory protocols.

Results

We have developed a web-based application allowing direct upload of sequences from multiple virome samples using custom parameters. The samples are then processed in parallel using an identical protocol, and can be easily reanalyzed. The pipeline performs de-novo assembly, taxonomic classification of viruses as well as sample analyses based on user-def

SUBMITTER: Lin J 

PROVIDER: S-EPMC5430618 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature