Exhaled breath condensate to discriminate individuals with different smoking habits by GC-TOF/MS.

ABSTRACT: Smoking is a crucial factor in respiratory diseases and lung inflammation, which are the reasons for high mortality worldwide. Despite the negative impact that tobacco consumption causes on health, few metabolomics studies have compared the composition of biofluids from smoker and non-smoker individuals. Exhaled breath condensate (EBC) is one of the biofluids less employed for clinical studies despite its non-invasive sampling and the foreseeable relationship between its composition and respiratory diseases. EBC was used in this research as clinical sample to compare three groups of individuals: current smokers (CS), former smokers (FS) and never smokers (NS). Special attention was paid to the cumulative consumption expressed as smoked pack-year. The levels of 12 metabolites found statisti

SUBMITTER: Peralbo-Molina A 

PROVIDER: S-EPMC5431160 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature