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Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid.

ABSTRACT: The one-step dehydration, decarboxylation and hydrogenation of the bio-based and widely available citric acid is presented. This reaction sequence yields methylsuccinic acid with yields of up to 89%. Optimal balances between the reaction rates of the different steps were found by varying the hydrogenation catalyst and the reaction parameters (H₂ pressure, pH, temperature, time and catalyst-to-substrate ratio).

SUBMITTER: Verduyckt J

PROVIDER: S-EPMC5431699 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Highly selective one-step dehydration, decarboxylation and hydrogenation of citric acid to methylsuccinic acid.

Verduyckt Jasper J De Vos Dirk E DE

Chemical science 20170116 4

The one-step dehydration, decarboxylation and hydrogenation of the bio-based and widely available citric acid is presented. This reaction sequence yields methylsuccinic acid with yields of up to 89%. Optimal balances between the reaction rates of the different steps were found by varying the hydrogenation catalyst and the reaction parameters (H2 pressure, pH, temperature, time and catalyst-to-substrate ratio). ...[more]

PMID: 28553496

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