Electrocorticographic delineation of human auditory cortical fields based on effects of propofol anesthesia.

ABSTRACT: The functional organization of human auditory cortex remains incompletely characterized. While the posteromedial two thirds of Heschl's gyrus (HG) is generally considered to be part of core auditory cortex, additional subdivisions of HG remain speculative. To further delineate the hierarchical organization of human auditory cortex, we investigated regional heterogeneity in the modulation of auditory cortical responses under varying depths of anesthesia induced by propofol. Non-invasive studies have shown that propofol differentially affects auditory cortical activity, with a greater impact on non-core areas. Subjects were neurosurgical patients undergoing removal of intracranial electrodes placed to identify epileptic foci. Stimuli were 50Hz click trains, presented continuously during an a

SUBMITTER: Nourski KV 

PROVIDER: S-EPMC5432407 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature