Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer.

ABSTRACT:

Objective

To investigate the effects of oral zinc supplementation on fatigue intensity and quality of life of patients during chemotherapy for colorectal cancer.

Methods

A prospective, randomized, double-blinded, placebo-controlled study was conducted with 24 patients on chemotherapy for colorectal adenocarcinoma in a tertiary care public hospital. The study patients received zinc capsules 35mg (Zinc Group, n=10) or placebo (Placebo Group, n=14) orally, twice daily (70mg/day), for 16 weeks, from the immediate postoperative period to the fourth chemotherapy cycle. Approximately 45 days after surgical resection of the tumor, all patients received a chemotherapeutic regimen. Before each of the four cycles of chemotherapy, the Functional Assessment of Chronic Illness Therapy-Fat

SUBMITTER: Ribeiro SMF 

PROVIDER: S-EPMC5433302 | biostudies-literature | 2017 Jan-Mar

REPOSITORIES: biostudies-literature