The relationship between objective parameters of sleep and measures of fatigue, depression, and cognition in multiple sclerosis.

ABSTRACT:

Background

People with multiple sclerosis (MS) often report poor sleep, fatigue, sleepiness, depression and cognitive dysfunction. Interrelationships between symptoms and sleep are poorly understood.

Objectives

To document objective parameters of sleep measured by polysomnography (PSG) and multi-sleep latency tests (MSLTs) in patients experiencing fatigue or sleepiness and to determine whether they correlate with symptoms.

Methods

Thirty-two MS patients, not on therapy, with fatigue or sleepiness completed the Modified Fatigue Impact Scale, Fatigue Severity Scale, Epworth Sleepiness Scale, Beck Depression Index and NeuroTrax cognitive tests and underwent PSG and MSLTs.

Results

Sleep efficiency (SE) averaged 75.1%. wake after sleep onset (WASO), sleep onset late

SUBMITTER: Sater RA 

PROVIDER: S-EPMC5433423 | biostudies-literature | 2015 Jan-Dec

REPOSITORIES: biostudies-literature