The effect of platelet-rich plasma on osseous healing in dogs undergoing high tibial osteotomy.

ABSTRACT:

Objectives

The purpose of this study was to investigate whether platelet-rich plasma (PRP) enhances osseous healing in conjunction with a high tibial osteotomy in dogs.

Study design

Randomized controlled trial.

Methods

Sixty-four client-owned pet dogs with naturally occurring rupture of the anterior cruciate ligament and that were to be treated with a high tibial osteotomy (tibial plateau leveling osteotomy) were randomized into the treatment or control group. Dogs in the treatment group received autologous platelet-rich plasma activated with calcium chloride and bovine thrombin to produce a well-formed PRP gel that was placed into the osteotomy at the time of surgery. Dogs in the control group received saline lavage of the osteotomy. All dogs had the osteotomy stabil

SUBMITTER: Franklin SP 

PROVIDER: S-EPMC5433731 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature