How does motion affect GABA-measurements? Order statistic filtering compared to conventional analysis of MEGA-PRESS MRS.

ABSTRACT:

Purpose

The aim of this study was to evaluate two post-processing techniques applied to MRS MEGA-PRESS data influenced by motion-induced artifacts. In contrast to the conventional averaging technique, order statistic filtering (OSF) is a known method for artifact reduction. Therefore, this method may be suitable to incorporate in the GABA quantification.

Methods

Twelve healthy volunteers were scanned three times using a 3 T MR system. One measurement protocol consisted of two MEGA-PRESS measurements, one reference measurement and one measurement including head motions. The resulting datasets were analyzed with the standard averaging technique and with the OSF-technique in two schemes; filtering phase cycles 'RAW PC' and filtering dynamics 'RAW Dyn'.

Results

The datase

SUBMITTER: Tapper S 

PROVIDER: S-EPMC5433745 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature