Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment.

ABSTRACT:

Importance

Most cognitive functions decline with age. Prior studies suggest that testosterone treatment may improve these functions.

Objective

To determine if testosterone treatment compared with placebo is associated with improved verbal memory and other cognitive functions in older men with low testosterone and age-associated memory impairment (AAMI).

Design, setting, and participants

The Testosterone Trials (TTrials) were 7 trials to assess the efficacy of testosterone treatment in older men with low testosterone levels. The Cognitive Function Trial evaluated cognitive function in all TTrials participants. In 12 US academic medical centers, 788 men who were 65 years or older with a serum testosterone level less than 275 ng/mL and impaired sexual function, physical

SUBMITTER: Resnick SM 

PROVIDER: S-EPMC5433758 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature