Cardiovascular risk factors in Chiari malformation and idiopathic intracranial hypertension.

ABSTRACT:

Objectives

Both Chiari malformation type 1 (CMI, i.e., the idiopathic caudal ectopy of cerebellar tonsils into foramen magnum) and idiopathic intracranial hypertension (IIH) are characterized by reduced intracranial compliance (ICC) due to disturbed circulation of cerebrospinal fluid (CSF). An increasing body of evidence links cardiovascular disease to CSF circulation disturbances. The aim of this study was to explore whether the prevalence of cardiovascular risk factors in patients with CMI or IIH is higher than in the general population.

Materials and methods

Among the patients with CMI or IIH treated at our department during the period 2003-2014, we identified those with history of arterial hypertension (AH), myocardial infarction (MI), angina pectoris (AP), or diabetes m

SUBMITTER: Fric R 

PROVIDER: S-EPMC5434183 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature