Systematic review of the potential role of cannabinoids as antiproliferative agents for urological cancers.

ABSTRACT: INTRODUCTION:The palliative effects of cannabis sativa (marijuana), which include appetite stimulation, attenuation of nausea and emesis, and pain relief, are well known. The active components of cannabis sativa (cannabinoids) and their derivatives have received growing interest due to their diverse pharmacological activities, such as cell growth inhibition and tumour regression. The aim of this review is to look at the current evidence on the antiproliferative effects of cannabinoids in urological malignancies, including renal, prostate, bladder, and testicular cancers. METHODS:We conducted a systematic review of studies exploring the effect of cannabinoids on tumour activity, including all study types except expert opinions. A formal search was run on Medline database from 1946 to Septem

SUBMITTER: Gandhi S 

PROVIDER: S-EPMC5434502 | biostudies-literature | 2017 Mar-Apr

REPOSITORIES: biostudies-literature