Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity.

ABSTRACT:

Background

The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers of The Environmental Determinants of Diabetes in the Young (TEDDY) prospective cohort study and test if ANAP use was a risk factor for islet autoimmunity.

Methods

Data were collected for 8542 children in the first 2.5 years of life. Incidence was analyzed using logistic regression with country and first child status as independent variables. Holm's procedure was used to adjust for mul

SUBMITTER: Lundgren M 

PROVIDER: S-EPMC5434629 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature