Paternal transmission of complex phenotypes in inbred mice.

ABSTRACT:

Background

Inbred mice are genetically identical but nonetheless demonstrate substantial variability in complex behaviors such as activity levels in a novel environment. This variability has been associated with levels of parental care experienced early in development. Although maternal effects have been reported in biparental and uniparental strains, there have been no investigations of paternal effects in non-biparental strains in which offspring are reared exclusively by mothers.

Methods

In the uniparental inbred Balb/cJ mouse strain, we examined the relationship of paternal open-field activity to the activity of both male and female offspring in the open-field. Potential mediators of paternal transmission of behavior were examined, including maternal care, growth paramet

SUBMITTER: Alter MD 

PROVIDER: S-EPMC5434703 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature