The 'cognitive footprint' of psychiatric and neurological conditions: cross-sectional study in the UK Biobank cohort.

ABSTRACT:

Objective

We aimed to quantify the prevalence of cognitive impairment in adults with a history of mood disorder, schizophrenia, multiple sclerosis or Parkinson's disease, within a large general population cohort.

Method

Cross-sectional study using UK Biobank data (n = 502 642). Psychiatric and neurological exposure status was ascertained via self-reported diagnoses, hospital records and questionnaires. Impairment on reasoning, reaction time and memory tests was defined with reference to a single unexposed comparison group. Results were standardised for age and gender. Sensitivity analyses examined the influence of comorbidity, education, information sources and missing data.

Results

Relative to the unexposed group, cognitive impairment was least common in major depres

SUBMITTER: Cullen B 

PROVIDER: S-EPMC5434825 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature