Pathway from Delirium to Death: Potential In-Hospital Mediators of Excess Mortality.

ABSTRACT:

Objectives

(1) To determine the relationship of incident delirium during hospitalization with 90-day mortality; (2) to identify potential in-hospital mediators through which delirium increases 90-day mortality.

Design

Analysis of data from Project Recovery, a controlled clinical trial of a delirium prevention intervention from 1995 to 1998 with follow-up through 2000.

Setting

Large academic hospital.

Participants

Patients ≥70 years old without delirium at hospital admission who were at intermediate-to-high risk of developing delirium and received usual care only.

Measurements

(1) Incident delirium; (2) potential mediators of delirium on death including use of restraining devices (physical restraints, urinary catheters), development of hospital acquired c

SUBMITTER: Dharmarajan K 

PROVIDER: S-EPMC5435507 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature