Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study.

ABSTRACT:

Objectives

To assess whether randomization to 10 years of lifestyle intervention to induce and maintain weight loss improves cognitive function.

Design

Randomized controlled clinical trial.

Setting

Data obtained as part of the Action for Health in Diabetes (Look AHEAD) trial (NCT00017953) and Look AHEAD Continuation study (U01 DK057136-15).

Participants

Overweight and obese individuals with type 2 diabetes mellitus aged 45 to 76 (N = 3,751).

Intervention

Intensive lifestyle intervention (ILI) for weight loss through reduced caloric intake and increased physical activity compared with a control condition of diabetes support and education (DSE).

Measurements

Certified examiners who were masked to intervention assignment administered a standard batte

SUBMITTER: Rapp SR 

PROVIDER: S-EPMC5435531 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature