Evaluation of the Sepsis Flow Chip assay for the diagnosis of blood infections.

ABSTRACT:

Background

Blood infections are serious complex conditions that generally require rapid diagnosis and treatment. The big challenge is to reduce the time necessary to make a diagnosis with current clinical microbiological methods so as to improve the treatment given to patients.

Methods

In this study, we assess for the first time the Sepsis Flow Chip assay, which is a novel diagnostic assay for simultaneous rapid-detection of the vast majority of bloodstream pathogens, including Gram-positive and Gram-negative bacteria and fungi, in the same assay, and for the detection of most common antibiotic resistance genes. The SFC assay is based on multiplex PCR and low density DNA arrays.

Results

Positive blood cultures from 202 consecutive bacteremia patients were analyzed by

SUBMITTER: Galiana A 

PROVIDER: S-EPMC5436663 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature