External validation of SAPS 3 and MPM0-III scores in 48,816 patients from 72 Brazilian ICUs.

ABSTRACT: BACKGROUND:The performance of severity-of-illness scores varies in different scenarios and must be validated prior of being used in a specific settings and geographic regions. Moreover, models' calibration may deteriorate overtime and performance of such instruments should be reassessed regularly. Therefore, we aimed at to validate the SAPS 3 in a large contemporary cohort of patients admitted to Brazilian ICUs. In addition, we also compared the performance of the SAPS 3 with the MPM0-III. METHODS:This is a retrospective cohort study in which 48,816 (medical admissions = 67.9%) adult patients are admitted to 72 Brazilian ICUs during 2013. We evaluated models' discrimination using the area under the receiver operating characteristic curve (AUROC). We applied the calibration belt to evaluate

SUBMITTER: Moralez GM 

PROVIDER: S-EPMC5436994 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature