Comparative genomic analysis of innate immunity reveals novel and conserved components in crustacean food crop species.

ABSTRACT:

Background

Growing global demands for crustacean food crop species have driven large investments in aquaculture research worldwide. However, large-scale production is susceptible to pathogen-mediated destruction particularly in developing economies. Thus, a thorough understanding of the immune system components of food crop species is imperative for research to combat pathogens.

Results

Through a comparative genomics approach utilising extant data from 55 species, we describe the innate immune system of the class Malacostraca, which includes all food crop species. We identify 7407 malacostracan genes from 39 gene families implicated in different aspects of host defence and demonstrate dynamic evolution of innate immunity components within this group. Malacostracans have achi

SUBMITTER: Lai AG 

PROVIDER: S-EPMC5437397 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature