DbcAMP regulates adipogenesis in sheep inguinal preadipocytes.

ABSTRACT:

Background

The cyclic adenosine-monophosphate (cAMP) pathway is generally recognized as one of the essential pathways for the adipose conversion of rodent preadipocytes in vitro. However, divergent effects of cAMP on adipocyte differentiation have also been reported. Since there is very little data on non-rodent preadipose cells, the aim of the present work was to analyze the effects of one classic activator (dbcAMP) of the cAMP pathway on the proliferation and differentiation of sheep preadipocytes grown.

Method

We retrospectively analyzed the regulation of dbcAMP on the proliferation and differentiation of sheep preadipocytes through observation on cell dynamic morphology, drawing on the growth curve, Oil Red O staining and induction of cell differentiation.

Results

SUBMITTER: Kong D 

PROVIDER: S-EPMC5437410 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature