A Randomized, Single-Blind, Crossover Trial of Recovery Time in High-Flux Hemodialysis and Hemodiafiltration.

ABSTRACT:

Background

The choice between hemodiafiltration (HDF) or high-flux hemodialysis (HD) to treat end-stage kidney disease remains a matter of debate. The duration of recovery time after treatment has been associated with mortality, affects quality of life, and may therefore be important in informing patient choice. We aimed to establish whether recovery time is influenced by treatment with HDF or HD.

Study design

Randomized patient-blinded crossover trial.

Settings & participants

100 patients with end-stage kidney disease were enrolled from 2 satellite dialysis units in Glasgow, United Kingdom.

Intervention

8 weeks of HD followed by 8 weeks of online postdilution HDF or vice versa.

Outcomes

Posttreatment recovery time, symptomatic hypotension events, dialys

SUBMITTER: Smith JR 

PROVIDER: S-EPMC5438239 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature