Genetic and familial predisposition to rotator cuff disease: a systematic review.

ABSTRACT:

Background

Rotator cuff disease is a common disorder leading to shoulder pain and loss of function. Its etiology in atraumatic cases is uncertain and is likely to extend beyond repetitive microtrauma or overuse. Our objective was to determine whether there is a genetic or familial predisposition to rotator cuff disease.

Methods

A literature search of PubMed and Embase databases identified 251 citations. After review of the titles, abstracts, and full articles, 7 met our inclusion and exclusion criteria.

Results

Four studies assessed familial predisposition to rotator cuff disease. One of these demonstrated that siblings of an individual with a rotator cuff tear were more likely to develop a full-thickness tear and more likely to be symptomatic. A 5-year follow-up show

SUBMITTER: Dabija DI 

PROVIDER: S-EPMC5438768 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature