Steeper discounting of delayed rewards in schizophrenia but not first-degree relatives.

ABSTRACT: Excessive discounting of future rewards has been related to a variety of risky behaviors and adverse clinical conditions. Prior work examining delay discounting in schizophrenia suggests an elevated discount rate. However, it remains uncertain whether this reflects the disease process itself or an underlying genetic vulnerability, whether it is selective for delay discounting or reflects pervasive changes in decision-making, and whether it is driven by specific clinical dimensions such as cognitive impairment. Here we investigated delay discounting, as well as loss aversion and risk aversion, in three groups: schizophrenia (SZ), unaffected first-degree family members (FM), and controls without a family history of psychosis (NC). SZ had elevated discounting, without changes in loss aversion

SUBMITTER: Yu LQ 

PROVIDER: S-EPMC5438888 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature