CKD and Risk for Hospitalization With Infection: The Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Background

Individuals on dialysis therapy have a high risk for infection, but risk for infection in earlier stages of chronic kidney disease has not been comprehensively described.

Study design

Observational cohort study.

Setting & participants

9,697 participants (aged 53-75 years) in the Atherosclerosis Risk in Communities (ARIC) Study. Participants were followed up from 1996 to 1998 through 2011.

Predictors

Estimated glomerular filtration rate (eGFR) and urinary albumin-creatinine ratio (ACR).

Outcomes

Risk for hospitalization with infection and death during or within 30 days of hospitalization with infection.

Results

During follow-up (median, 13.6 years), there were 2,701 incident hospitalizations with infection (incidence rate, 23.6/1,000 per

SUBMITTER: Ishigami J 

PROVIDER: S-EPMC5438909 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature