Gene-Environment Interactions-What Can These Tell Us about the Relationship between Asthma and Allergy?

ABSTRACT: Asthma is a common condition, which is associated with atopy and allergic conditions including hay fever, eczema, and food allergies. Asthma and atopy are both complex conditions where genetic and environmental factors are implicated in causation. Interactions between genetic and environmental factors, likely via epigenetic mechanisms, are widely thought to be important in determining the risk for developing asthma and atopy. The nature of the relationship between asthma and atopy is unclear and the answer to the question "does atopy cause asthma?" remains unknown. This review explores the relationship between asthma and atopy from a gene-environment interaction perspective and tackles the question "are similar gene-environment interactions present for asthma and atopy?" The main fi

SUBMITTER: Turner S 

PROVIDER: S-EPMC5438974 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature