Maintenance of Remission with Partial Enteral Nutrition Therapy in Pediatric Crohn's Disease: A Retrospective Study.

ABSTRACT:

Background

Partial enteral nutrition (PEN) may be helpful for the maintenance of remission in pediatric Crohn's disease patients.

Aims

To evaluate the efficacy of PEN treatment for preventing clinical relapse.

Methods

We retrospectively assessed 42 pediatric Crohn's disease patients who entered clinical remission on 4-12 weeks of exclusive enteral nutrition (EEN) and were maintained on PEN as a supplementary diet. We evaluated the efficacy of the treatment at different time points using the weighted Pediatric Crohn Disease Activity Index (wPCDAI), Physician Global Assessment, laboratory parameters, and growth of each patient. Additionally, we assessed the use of concomitant medications.

Results

The median length of remission with PEN was 6 (0-36) months. Patien

SUBMITTER: Schulman JM 

PROVIDER: S-EPMC5439067 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature