Association of influenza vaccination during pregnancy with birth outcomes in Nicaragua.

ABSTRACT:

Background

Studies have shown that influenza vaccination during pregnancy reduces the risk of influenza disease in pregnant women and their offspring. Some have proposed that maternal vaccination may also have beneficial effects on birth outcomes. In 2014, we conducted an observational study to test this hypothesis using data from two large hospitals in Managua, Nicaragua.

Methods

We conducted a retrospective cohort study to evaluate associations between influenza vaccination and birth outcomes. We carried out interviews and reviewed medical records post-partum to collect data on demographics, influenza vaccination during pregnancy, birth outcomes and other risk factors associated with adverse neonatal outcomes. We used influenza surveillance data to adjust for timing of inf

SUBMITTER: Arriola CS 

PROVIDER: S-EPMC5439533 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature