Noninvasive positive pressure ventilation enhances the effects of aerobic training on cardiopulmonary function.

ABSTRACT:

Purpose

The purpose of this study was to determine the effect of aerobic training under noninvasive positive pressure ventilation (NPPV) on maximal oxygen uptake ([Formula: see text]).

Methods

Ten healthy young male volunteers participated in the study. Before the training, stroke volume (SV) and cardiac output (CO) were measured in all subjects under 0, 4, 8, and 12 cmH2O NPPV at rest. Then, the subjects exercised on a cycle ergometer at 60% of pre-training [Formula: see text] for 30 min daily for 5 consecutive days with/without NPPV. The 5-day exercise protocol was repeated after a three-week washout period without/with NPPV. The primary endpoint was changes in [Formula: see text]. The secondary endpoints were changes in SV, CO, maximum heart rate (HRmax), maximum respirat

SUBMITTER: Moriki T 

PROVIDER: S-EPMC5439726 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature