Association between common polymorphisms in ERCC gene and glioma risk: A meta-analysis of 15 studies.

ABSTRACT:

Background

A number of studies have investigated the roles of excision repair cross complementation group 1 (ERCC1), ERCC2, and ERCC5 genes polymorphisms in the development of glioma; however, the results were inconsistent. Here, we performed a meta-analysis to investigate the association between 6 polymorphisms in the ERCC genes (rs3212986, rs11615, rs13181, rs1799793, rs238406, rs17655) and glioma risk.

Methods

The PubMed, Embase, and Web of science were searched up to September 6, 2016, for studies on the association between ERCC polymorphisms and glioma risk. A fixed-effects or random-effects model was used to calculate the pooled odds ratios based on the results from the heterogeneity tests. Sensitivity and cumulative meta-analyses were also performed.

Results

A

SUBMITTER: Qian T 

PROVIDER: S-EPMC5440135 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature