Periodontitis and early mortality among adults treated with hemodialysis: a multinational propensity-matched cohort study.

ABSTRACT:

Background

Periodontitis is associated with cardiovascular mortality in the general population and adults with chronic diseases. However, it is unclear whether periodontitis predicts survival in the setting of kidney failure.

Methods

ORAL-D was a propensity matched analysis in 3338 dentate adults with end-stage kidney disease treated in a hemodialysis network in Europe and South America designed to examine the association between periodontitis and all-cause and cardiovascular-related mortality in people on long-term hemodialysis. Participants were matched 1:1 on their propensity score for moderate to severe periodontitis assessed using the World Health Organization Community Periodontal Index. A random-effects Cox proportional hazards model was fitted with shared frailty to

SUBMITTER: Ruospo M 

PROVIDER: S-EPMC5440912 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature