Ontology highlight
ABSTRACT:
SUBMITTER: Sergeyev IV
PROVIDER: S-EPMC5441803 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Sergeyev Ivan V IV Itin Boris B Rogawski Rivkah R Day Loren A LA McDermott Ann E AE
Proceedings of the National Academy of Sciences of the United States of America 20170501 20
An experimental strategy has been developed to increase the efficiency of dynamic nuclear polarization (DNP) in solid-state NMR studies. The method makes assignments simpler, faster, and more reliable via sequential correlations of both side-chain and Cα resonances. The approach is particularly suited to complex biomolecules and systems with significant chemical-shift degeneracy. It was designed to overcome the spectral congestion and line broadening that occur due to sample freezing at the cryo ...[more]