Outcomes after inappropriate nuclear myocardial perfusion imaging: A meta-analysis.

ABSTRACT:

Background

The relationship between inappropriate MPI and cardiovascular outcomes is poorly understood. We sought to systematically review the literature on appropriate use criteria (AUC) for MPI, including temporal trend of inappropriate testing and resulting cardiovascular outcomes.

Methods

We searched the MEDLINE database for studies related to AUC and MPI. The co-primary outcomes were abnormal test results and the presence of cardiac ischemia. Random effects odds ratios (OR) were constructed using DerSimonian-Laird method.

Results

A total of 22 studies with 23,443 patients were included. The prevalence of inappropriate testing was 14.8% [95% confidence interval (CI) 11.6%-18.7%]. Inappropriate MPI studies were less likely to be abnormal (OR 0.41 95% CI 0.35-0.49,

SUBMITTER: Elgendy IY 

PROVIDER: S-EPMC5442883 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature