Association between mixed rotavirus vaccination types of infants and rotavirus acute gastroenteritis.

ABSTRACT:

Introduction

Rotavirus remains the leading cause of severe diarrhea in children under 5 years worldwide. In the US, Rotarix (RV1) and RotaTeq (RV5), have been associated with reductions in and severity of rotavirus disease. Studies have evaluated the impact of RV1 or RV5 but little is known about the impact of incomplete or mixed vaccination upon vaccine effectiveness.

Methods

Case control study to examine association of combined RV1 and RV5 and rotavirus acute gastroenteritis, factoring severity of diarrheal disease. Children born after March 1, 2009 with acute gastroenteritis from three pediatric hospitals in Atlanta, Georgia were approached for enrollment. Survey was administered, stool specimen was collected, and vaccination records were obtained.

Results

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SUBMITTER: Mohammed A 

PROVIDER: S-EPMC5444377 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature