Prenatal Exposure to Perfluoroalkyl Substances and Body Fatness in Girls.

ABSTRACT:

Background

Perfluoroalkyl substances (PFASs) are used in surface coatings that resist stains, grease, and water.

Methods

The association between in utero PFAS exposure and girls' body fatness at age 9 was analyzed in The Avon Longitudinal Study of Parents and Children (UK). Maternal serum [median 15 weeks: interquartile range (IQR) 10 and 28 weeks of gestation] was analyzed for perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexane sulfonate (PFHxS), and perfluorononanoate (PFNA). Body composition was measured by dual X-ray emission absorptiometry, and percent total body fat (%BF) was calculated. Associations between PFASs and body fatness were modeled by multivariable linear regression.

Results

Among 359 girls, median (IQR) %BF was 27.5 (IQR 21.

SUBMITTER: Hartman TJ 

PROVIDER: S-EPMC5444423 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature