Guillain-Barre Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study.

ABSTRACT:

Background

Between October, 2013, and April, 2014, French Polynesia experienced the largest Zika virus outbreak ever described at that time. During the same period, an increase in Guillain-Barré syndrome was reported, suggesting a possible association between Zika virus and Guillain-Barré syndrome. We aimed to assess the role of Zika virus and dengue virus infection in developing Guillain-Barré syndrome.

Methods

In this case-control study, cases were patients with Guillain-Barré syndrome diagnosed at the Centre Hospitalier de Polynésie Française (Papeete, Tahiti, French Polynesia) during the outbreak period. Controls were age-matched, sex-matched, and residence-matched patients who presented at the hospital with a non-febrile illness (control group 1; n=98) and age-matched p

SUBMITTER: Cao-Lormeau VM 

PROVIDER: S-EPMC5444521 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature