Comparing clinical presentations, treatments and outcomes of hepatocellular carcinoma due to hepatitis C and non-alcoholic fatty liver disease.

ABSTRACT:

Introduction

Hepatocellular carcinoma (HCC) is increasing in incidence in the UK and globally. Liver cirrhosis is the common cause for developing HCC. The common reasons for liver cirrhosis are viral hepatitis C (HCV), viral hepatitis B and alcohol. However, HCC caused by non-alcoholic fatty liver disease (NAFLD)-cirrhosis is now increasingly as a result of rising worldwide obesity.

Aim

: To compare the clinical presentation, treatment options and outcomes of HCC due to HCV and NAFLD patients.

Methods

Data were collected from two liver transplant centres in the UK (Birmingham and Newcastle upon Tyne) between 2000 and 2014. We compared 275 patients with HCV-related HCC against 212 patients with NAFLD- related HCC.

Results

Patients in the NAFLD group were found t

SUBMITTER: Than NN 

PROVIDER: S-EPMC5444673 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature