Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry.

ABSTRACT:

Background

Soy foods possess both antiestrogenic and estrogen-like properties. It remains controversial whether women diagnosed with breast cancer should be advised to eat more or less soy foods, especially for those who receive hormone therapies as part of cancer treatment.

Methods

The association of dietary intake of isoflavone, the major phytoestrogen in soy, with all-cause mortality was examined in 6235 women with breast cancer enrolled in the Breast Cancer Family Registry. Dietary intake was assessed using a Food Frequency Questionnaire developed for the Hawaii-Los Angeles Multiethnic Cohort among 5178 women who reported prediagnosis diet and 1664 women who reported postdiagnosis diet. Cox proportional-hazard models were used to estimate hazard ratios (HRs) and 95% conf

SUBMITTER: Zhang FF 

PROVIDER: S-EPMC5444962 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature