Computational fluid dynamics and trigeminal sensory examinations of empty nose syndrome patients.

ABSTRACT:

Objective

The precise pathogenesis of empty nose syndrome (ENS) remains unclear. Various factors such as nasal aerodynamics and sensorineural dysfunction have been suspected, although evidence is limited. This study reported the first examination of both nasal aerodynamics and trigeminal sensory factors in actual ENS patients.

Study design

Prospective case control.

Methods

We enrolled six patients diagnosed with ENS. Three patients had pre- and post-inferior turbinate (IT) reduction computed tomography scans, which allowed comparison of their nasal aerodynamics changes through computational fluid dynamic (CFD) simulation. Their symptoms were confirmed through Sino-nasal Outcome Test-22, ENS 6-item Questionnaire, acoustic rhinometry, and rhinomanometry findings. Nasal

SUBMITTER: Li C 

PROVIDER: S-EPMC5445013 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature