Quantifying the global contribution of alcohol consumption to cardiomyopathy.

ABSTRACT:

Background

The global impact of alcohol consumption on deaths due to cardiomyopathy (CM) has not been quantified to date, even though CM contains a subcategory for alcoholic CM with an effect of heavy drinking over time as the postulated underlying causal mechanism. In this feasibility study, a model to estimate the alcohol-attributable fraction (AAF) of CM deaths based on alcohol exposure measures is proposed.

Methods

A two-step model was developed based on aggregate-level data from 95 countries, including the most populous (data from 2013 or last available year). First, the crude mortality rate of alcoholic CM per 1,000,000 adults was predicted using a negative binomial regression based on prevalence of alcohol use disorders (AUD) and adult alcohol per capita consumption (

SUBMITTER: Manthey J 

PROVIDER: S-EPMC5445448 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature