Sudden versus gradual pressure wean from Nasal CPAP in preterm infants: a randomized controlled trial.

ABSTRACT:

Objective

In preterm infants, nasal continuous positive airway pressure (NCPAP) is widely used for treatment of respiratory distress syndrome. However, the strategies for successfully weaning infants off NCPAP are still not well defined and there remains considerable variation between the methods. The objective of this study is to determine whether gradual weaning of NCPAP pressure is more successful than sudden weaning off NCPAP to room air.

Study design

A randomized controlled trial was conducted in a level 3 neonatal intensive care unit on 70 preterm neonates who were born between 26 and 32 weeks gestation and required NCPAP for at least 48 h. When infants were stable on NCPAP at 0.21 FiO₂ and 5 cm H₂O positive end expiratory pressure, neonates were

SUBMITTER: Amatya S 

PROVIDER: S-EPMC5446290 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature