Scale-integrated Network Hubs of the White Matter Structural Network.

ABSTRACT: The 'human connectome' concept has been proposed to significantly increase our understanding of how functional brain states emerge from their underlying structural substrates. Especially, the network hub has been considered one of the most important topological properties to interpret a network as a complex system. However, previous structural brain connectome studies have reported network hub regions based on various nodal resolutions. We hypothesized that brain network hubs should be determined considering various nodal scales in a certain range. We tested our hypothesis using the hub strength determined by the mean of the "hubness" values over a range of nodal scales. Some regions of the precuneus, superior occipital gyrus, and superior parietal gyrus in a bilaterally symmetric fashion

SUBMITTER: Kwon H 

PROVIDER: S-EPMC5446418 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature