Neural stem cell therapy for neurodegenerative disorders: The role of neurotrophic support.

ABSTRACT: Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease currently affect tens of millions of people worldwide. Unfortunately, as the world's population ages, the incidence of many of these diseases will continue to rise and is expected to more than double by 2050. Despite significant research and a growing understanding of disease pathogenesis, only a handful of therapies are currently available and all of them provide only transient benefits. Thus, there is an urgent need to develop novel disease-modifying therapies to prevent the development or slow the progression of these debilitating disorders. A growing number of pre-clinical studies have suggested that transplantation of neural stem cells (NSCs) could offer a promising new therapeutic a

SUBMITTER: Marsh SE 

PROVIDER: S-EPMC5446923 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature