Functional and Structural Network Recovery after Mild Traumatic Brain Injury: A 1-Year Longitudinal Study.

ABSTRACT: Brain connectivity after mild traumatic brain injury (mTBI) has not been investigated longitudinally with respect to both functional and structural networks together within the same patients, crucial to capture the multifaceted neuropathology of the injury and to comprehensively monitor the course of recovery and compensatory reorganizations at macro-level. We performed a prospective study with 49 mTBI patients at an average of 5 days and 1 year post-injury and 49 healthy controls. Neuropsychological assessments as well as resting-state functional and diffusion-weighted magnetic resonance imaging were obtained. Functional and structural connectome analyses were performed using network-based statistics. They included a cross-sectional group comparison and a longitudinal analysis with the fa

SUBMITTER: Dall'Acqua P 

PROVIDER: S-EPMC5447750 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature