Intraoperative peritoneal lavage cytology offers prognostic significance for gastric cancer patients with curative resection.

ABSTRACT: Outcomes of patients with gastric cancer who exhibit positive peritoneal lavage cytology findings (CY⁺ ) vary by diagnostic methods because of quantitative and qualitative cancer cell diversity. This study sought to establish practical diagnostic criteria for performing curative resections, based on peritoneal lavage cytology findings in gastric cancer patients. We enrolled 1028 patients with gastric cancer who underwent R0/1 (n = 911) or R2 (n = 117) resections and analyzed relationships between cancer cell findings in peritoneal lavage fluid and clinicopathological factors in the R0/1 group. We found 68 patients with CY⁺ status. Receiver operating characteristic analyses and multivariate analyses showed that the presence of ≥1 signet ring cell, ≥5 cell clusters or ≥

SUBMITTER: Higaki E 

PROVIDER: S-EPMC5448654 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature