Timing of nicotine lozenge administration to minimize trigger induced craving and withdrawal symptoms.

ABSTRACT:

Introduction

Smokers are often advised to use nicotine lozenge when craving or withdrawal symptoms occur. This may be too late to prevent lapses. This study assessed if nicotine lozenge use prior to a common smoking trigger can minimize trigger induced increases in craving and withdrawal symptoms.

Methods

Eighty-four smokers completed two laboratory sessions in random order. At one session, nicotine lozenge was given immediately after a stressor (to approximate current recommended use - i.e., after craving and withdrawal symptoms occur); at the other session subjects were randomized to receive nicotine lozenge at time points ranging from immediately to 30min prior to the stressor. Withdrawal symptoms and urge to smoke were measured using the Minnesota Nicotine Withdrawal Sca

SUBMITTER: Kotlyar M 

PROVIDER: S-EPMC5449230 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature