Perioperative antibiotics in pediatric cardiac surgery: protocol for a systematic review.

ABSTRACT:

Background

Post-operative infections in pediatric cardiac surgery are an ongoing clinical challenge, with rates between 1 and 20%. Perioperative antibiotics remain the standard for prevention of surgical-site infections, but the type of antibiotic and duration of administration remain poorly defined. Current levels of practice variation through informal surveys are very high. Rates of antibiotic-resistant organisms are increasing steadily around the world.

Methods/design

We will identify all controlled observational studies and randomized controlled trials examining prophylactic antibiotic use in pediatric cardiac surgery. Data sources will include MEDLINE, EMBASE, CENTRAL, and proceedings from recent relevant scientific meetings. For each included study, we will conduct dup

SUBMITTER: Anand V 

PROVIDER: S-EPMC5450342 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature