Background anaesthetic agents do not influence the impact of arginine vasopressin on haemodynamic states and cerebral oxygenation during shoulder surgery in the beach chair position: a prospective, single-blind study.

ABSTRACT:

Background

Administration of arginine vasopressin (AVP) is associated with reducing jugular venous (SjvO₂) and regional cerebral (rScO₂) oxygen saturation under propofol-remifentanil (P/R) anaesthesia. We determined whether background anaesthetics modulate the effect of AVP on cerebral oxygenation and haemodynamics.

Methods

We randomly allocated 60 adult patients scheduled for shoulder surgery in the beach chair position (BCP) into 4 groups, to receive either an intravenous bolus of saline (groups PR-S and SN-S) or 0.05 U/kg AVP (groups PR-AVP and SN-AVP) under P/R or sevoflurane-nitrous oxide (S/N) anaesthesia (n = 15 each). Haemodynamic variables, SjvO₂ and rScO₂ were measured.

Results

AVP significantly increased mean arte

SUBMITTER: Jang EA 

PROVIDER: S-EPMC5450390 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature