Every antibiotic, every day: Maximizing the impact of prospective audit and feedback on total antibiotic use.

ABSTRACT:

Background

The success of antimicrobial stewardship is dependent on how often it is completed and which antimicrobials are targeted. We evaluated the impact of an antimicrobial stewardship program (ASP) in three non-ICU settings where all systemic antibiotics, regardless of spectrum, were targeted on the first weekday after initiation.

Methods

Prospective audit and feedback (PAAF) was initiated on the surgical, respiratory, and medical wards of a community hospital on July 1, 2010, October 1, 2010, and April 1, 2012, respectively. We evaluated rates of total antibiotic use, measured in days on therapy (DOTs), among all patients admitted to the wards before and after PAAF initiation using an interrupted time series analysis. Changes in antibiotic costs, rates of C. difficile

SUBMITTER: Campbell TJ 

PROVIDER: S-EPMC5451052 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature