Family cord blood banking for sickle cell disease: a twenty-year experience in two dedicated public cord blood banks.

ABSTRACT: Efforts to implement family cord blood banking have been developed in the past decades for siblings requiring stem cell transplantation for conditions such as sickle cell disease. However, public banks are faced with challenging decisions about the units to be stored, discarded, or used for other endeavors. We report here 20 years of experience in family cord blood banking for sickle cell disease in two dedicated public banks. Participants were pregnant women who had a previous child diagnosed with homozygous sickle cell disease. Participation was voluntary and free of charge. All mothers underwent mandatory serological screening. Cord blood units were collected in different hospitals, but processed and stored in two public banks. A total of 338 units were stored for 302 families. Median r

SUBMITTER: Rafii H 

PROVIDER: S-EPMC5451329 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature