Association between blood pressure and Alzheimer disease measured up to 27 years prior to diagnosis: the HUNT Study.

ABSTRACT:

Background

A lot of attention has been paid to the relationship of blood pressure and dementia because epidemiological research has reported conflicting evidence. Observational data has shown that midlife hypertension is a risk factor for cognitive decline and dementia later in life, whereas there is evidence that low blood pressure is predictive in later life. The aim of the present study was to examine the association between dementia and blood pressure measured up to 27 years (mean 17.6 years) prior to ascertainment.

Methods

In Nord-Trøndelag County, Norway, incident dementia data were collected during 1995-2011, and the diagnoses were validated by a panel of experts in the field. By using the subjects' personal identification numbers, the dementia data were linked to dat

SUBMITTER: Gabin JM 

PROVIDER: S-EPMC5452294 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature